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1、JournalofPublicHealthResearch2016;volume5:733ArticlePrevalenceofdiabetesinthe2009influenzaA(H1N1)andtheMiddleEastrespiratorysyndromecoronavirus:asystematicreviewandmeta-analysisAlaaBadawi,1SeungGwanRyoo21PublicHealthRiskSciencesDivision,PublicHealthAgency

2、ofCanada,Toronto,ON;2FacultyofArtsandScience,UniversityofToronto,Toronto,ON,CanadaSignificanceforpublichealthIntroductionOutbreaksofthe2009influenzaA(H1N1)andtheMiddleEastrespira-torysyndromecoronavirus(MERS-CoV)havepresentedaconsiderableForthepasttwodeca

3、des,pandemicsofsevereacuterespiratoryglobalpublichealththreatoverthepastfewyears.Evidencesuggestinfections(SARI)havebeenseriousthreatstoglobalhealth,causingthatinfectedsubjectswhoarealsodiabeticaremorelikelytobesuscep-significantmorbidityandmortality.Reas

4、sortednovelstrainsoftibletosevereoutcomeofH1N1andMERS-CoV.Systematicanalysisofinfluenzavirusesandcoronavirusescontinuetoarise,renderingvac-~93,000H1N1casesand~300MERS-CoVcasesindicatedanoverallcinations-ifdeveloped-lessusefulandposingincreasedriskstopreva

5、lenceof14.6%and54.4%fordiabetesinH1N1andMERS-CoVhumans.Twoprominentviruses–2009influenzaA(H1N1)andthecases,respectively.ThismaysuggestapossibleetiologicalrelationshipMiddleEastrespiratorysyndromecoronavirus(MERS-CoV)–haveonlybetweendiabetesandeachofthetwo

6、infectiousconditions.markedlyaffectedhumans.H1N1,sincethe2009pandemic,hasIntroductionofeffectivepublichealthvaccinationinterventionstrate-causedabout284,500deaths,bothdirectlyviarespiratoryinfectionsgiesagainstsevereacuterespiratoryinfectionsshouldbedevel

7、opedtoandindirectlyfromthecardiovasculardiseasessecondarytobacterialtargetsubjectswithchronicdisorderssuchasdiabetes,obesityandcar-diovascularconditions.infections.1Inaddition,MERS-CoV,sinceitsfirstemergencein2012,usehasinfected1600individuals,causing574d

8、eathsandwasreportedin26countriesalthoughthevastmajorityofreportedcasesoriginatedfromtheArabianPeninsula.2H1N1andMERS-CoVbothtargettherespiratorytract,andshareAbstractmanysimilarclinicalsymptoms.Themostcommonsymptoms