《The Role of Subchondral Bone in Joint Disease軟骨下骨在關(guān)節(jié)疾病中的作用》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫。

1、ReprintedintheIVISwebsitewiththepermissionofAAEPClosewindowtoreturntoIVISINDEPTH:CURRENTCONCEPTSINEQUINEOSTEOARTHRITISTheRoleofSubchondralBoneinJointDiseaseChristopherE.Kawcak,DVM,PhD,DiplomateACVS;C.WayneMcIlwraith,BVSc,PhD,FRCVS,DiplomateACVS;RichardD.Park,DVM,PhD;andS.P.James,PhDThereis

2、evidencetosuggestthatosteochondraldiseasesintheathletichorsestartaschronicprocesseswhichculminateinclinicaldisease.Authors'addresses:EquineOrthopaedicResearchLaboratory(KawcakandMcIlwraith),DepartmentofRadiologicalHealthSciences(Park),CollegeofVeterinaryMedicineandBiomedicalSciences,andDep

3、artmentofMechanicalEngineering(James),CollegeofEngineering,ColoradoStateUniversity,FortCollins,CO80523.?2001AAEP.1.IntroductionderstandingofosteochondraldiseaseisbasedonSubchondralboneplaysaroleinthepathogenesisofclinicalandpathologicsources,andthatthelackofosteochondraldamageandosteoarthr

4、itisinhorsesinformationaboutjointtissueadaptationanddis-andhumans.Osteochondralfragmentationandeasehashamperedobjectivestudiesofosteochon-draltissues.fracture,subchondralbonenecrosis,andosteoar-thritisarecommondiseasesinathletichorses,andsubchondralboneisnowthoughttoplayanintegral2.Osteoch

5、ondralTissuesroleinthepathogenesisofthesediseases.ThereThetissuesthatcomposeandsupportjointsurfaceshavebeennumerousresearcheffortsfocusedonar-arecollectivelycalledosteochondraltissues.Theticularcartilagedamageanditspathogenesis,yetmostsuper?cialofthese,thearticularcartilage,iscomparatively

6、littleefforthasbeenfocusedonsub-essentialforabsorbingshockandmaintainingnor-chondralbonepathology,orthecoordinateddiseasemaljointenvironment,and,regardlessofthecause,statesoftheosteochondraltissues.Thepurposeofdegenerationofarticularcartilagecanresultinir-1thisreportistoreviewthecurrentund

7、erstandingreversibleosteoarthritis.Thesubarticulartissuesofosteochondraldiseaseinallspeciesanditsap-includecalci?edcartilage,whichprovidesatransi-plicationtoequineresearchandpractice.Itcanbetionbetweenthestiffsubchondralboneandtheconcludedfromthisreviewthatour